An Engineering Research Center Focused on Revolutionizing Metallic Biomaterials

A collaborative engineering research center (ERC) funded by the NSF is focused on realizing the potential for metallic materials to be utilized in regenerative medicine. Whereas current metallic biomaterials are selected for their resistance to corrosion, in addition to mechanical properties, biocompatibility and processability, regenerative medicine seeks to harness the body’s potential for functional healing, ideally without permanent foreign body placement. Magnesium and iron based alloys offer the potential for temporary mechanical support in vivo and might be coupled with other regenerative medicine strategies, such as controlled release of pharmaceutical agents, to facilitate functional outcomes in a variety of disease states. This ERC seeks to expand the repertoire and knowledge-base regarding degradable metals for medical device application and is comprised of projects spanning alloy design and characterization, processing, coatings and specific medical device development for orthopedic, cardiothoracic and neural applications.