Increased service requirements for the current military aircraft fleet are extending lifetimes and environmental exposure beyond design criteria. It is critical that corrosion is detected before structural integrity is compromised and repair becomes economically prohibitive. One approach to corrosion monitoring is to measure the environmental species required for corrosion, such as moisture, and environmental parameters that influence corrosion kinetics, such as temperature. Novel optical fiber-based sensors for real-time monitoring of these and other environmental parameters have been developed. In addition, a prototype 8-channel instrumentation system has been developed to demonstrate operation of the fiber optic sensors during flight. The flight-qualified ulti-channel instrument is a multi-purpose platform that can operate numerous fiber optic sensors types. As an intial demonstration, humidity, pressure and temperature sensors were installed in a commercial airliner. Development and evaluation of the sensors and instrumentation are presented and discussed.