Computer simulation modeling has become mainstream in many industries. Finite element analysis (FEA) and computational fluid dynamics (CFD) are used extensively to develop and validate designs of components and systems. Computer simulation modeling of nondestructive inspection (NDI) processes is a relatively new technology but the benefits of the technology are already being realized. Simulation methods include analytical formulations as well as finite element analysis. This paper will present some case studies of how simulation modeling is used to develop inspection procedures and inspection instrument designs. Benefits include reduced time to develop inspection processes, optimized inspection methods, ability to visualize beam-defect interactions which lends insight to the physics behind the process, and quick comparisons between different inspection techniques. Examples covering a range of NDI techniques will be presented. Future needs and directions will also be covered.