A step towards integral fuselage shells was the first series application of laser beam welding of stringers to the skin on a lower fuselage panel of the A318. This new approach is continued for the A380, where panels of the lower fuselage will also have laser beam welded skin/stringer joints. Successful introduction of welded fuselage structure into series production is strong justification for further development work to achieve full benefit of welded structures for future aircraft by targeted utilization of new alloys, design as well as manufacturing processes tailored for the new alloys. A key project for the development of such advanced technologies is the TANGO (Technology Application to the Near-Term Business Goals and Objectives) project, where four large primary airframe structures, the technology platforms (Composite lateral wingbox, Composite centre wingbox, Composite fuselage section, Advanced metallic fuselage section) have been developed, constructed and are being tested. This presentation focuses on advanced technologies for integral metallic fuselage structures. It gives an overview how various new materials and technologies are brought together into TANGO Metallic Fuselage barrel. Nearly every shell of the barrel is made up of different advanced materials and incorporates new design principles and manufacturing technologies as friction stir welding, laser beam welding, integrally stiffened extruded skin panels and innovative forming technologies. An overview of applied materials and metallic products as AlMgSc- or AlMgLi-sheets and stringers, their properties and advantages will be given. Processes and manufacturing steps for these advanced materials from preparation of skin sheets to the assembly of the barrel sections will be presented for selected panels. Finally, weight and cost reduction potential of the applied technologies will be summarized.