Alcoa anticipates that through the combination of advanced alloys, novel design and innovative manufacturing methods both the cost and weight of future aircraft structure can be significantly reduced compared to the current built-up structure of today. Alcoa internal trade studies are being conducted on wing structure to identify the alloy combinations and design and manufacturing concepts that demonstrate the most promising combination of both weight and cost reduction. For lower wing covers, the concepts investigated include new 2xxx and Al-Li alloys, selective reinforcement methods to increase the damage tolerance and residual strength of wing panels and integral structure. For upper covers, the concepts investigated include alloy considerations, integral structure, and cost effective ways to create large scale integral wing panels. This presentation will provide an overview of the design and manufacturing concepts, analysis methodologies used in the trade studies and trade study results, as well as conclusions as to how to apply the results to advanced wing structures.