Computational tools have transformed many fields of engineering and their use has accelerated product design processes.   However, a critical missing link in the integrated product development and manufacturing process is a full set of computational materials engineering tools. The fundamental technical challenge is that the structure and behavior of engineering materials involves a multitude of physical phenomena spanning many orders of magnitude in length and time.  While a comprehensive set of tools for materials are far from fully developed, it will be shown that integration of emerging models and information can have a substantial impact on design and manufacturing and implementation of new high temperature materials and processes.  Examples of the impact of materials modeling on metallic components in aerospace vehicles will be reviewed.  The development of some new materials characterization tools that support model development will be presented. Finally, future challenges for integrated computational materials engineering will be reviewed.