ATI 425^® Alloy is a recently developed alpha-beta titanium alloy with strength comparable to Ti 6Al-4V but with improved ductility and formability. Due to the unique combination of properties, ATI 425^® Alloy (AMS 6946) is becoming an attractive candidate for replacement of Ti 6Al-4V (AMS 4911) for aerospace structural applications as well as a potential upgrade from alloys such as Ti 3Al-2.5V (AMS 4989) and Ti CP-4 (AMS 4901). This presentation will focus on the effects of heat treat conditions on the damage tolerance properties of ATI 425^® Alloy hot rolled plate, including; toughness, tensile, crack growth, microstructure and fractographic response.