16.1 Development and Characterization of a Novel Biodegradable Polymer-Coated Titanium Alloys for Implant Applications

Wednesday, August 10, 2011: 10:40 AM
Salon B (Hilton Minneapolis )
Ms. Chandan Pulletikurthi , Florida International University, Miami, FL
Prof. N. Munroe , Florida International University, Miami, FL
Ms. S. Amruthaluri , Florida International University, Miami, FL
Dr. R. S. Bezwada , Bezwada Biomedical, LLC, Hillsborough, NJ
A significant amount of research has recently been devoted to the improvement of biodegradable polymer-coated implant materials in an effort to enhance their bioactive response.  Some polymer coatings have been developed to mitigate various deleterious effects associated with implants, such as biofilm formation, restenosis, late stent thrombosis and corrosion.  This investigation focused on assessing the biocompatibility of novel biodegradable polymer-coated implantable titanium alloys.  In-vitro biocompatibility studies including degradation and drug-eluting rates, cytotoxicity and cell proliferation were conducted.  Platelet adhesion tests were performed on the materials to assess their thrombogenicity.